Safety answer
Is it safe to delete node_modules?
Usually, yes. node_modules is generated by a JavaScript package manager. If the project still has its package files, you can normally reinstall dependencies later.
What to check first
Confirm the folder belongs to a project you recognize. Look for dependency files such as package.json and a lockfile. If you are actively working on the project, be ready to reinstall dependencies before running it again.
Why use Trash first?
Moving to Trash gives you a recovery window. If you deleted the wrong folder or need it immediately, you can restore it before emptying Trash.
How to do it with DevClean
Choose your project folder, scan, review every node_modules path, unselect anything you want to keep, then move the selected folders to Trash.